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ATROPINE SULPHATE MONOHYDRATE AR

(Confirms to IP) Store at 2-8°C
a-(Hydroxymethyl)benzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester; Tropine tropate

COAs

Packings

5 g (00005)

25 g (00025)

1GBA000015 1GBA000015
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Article No. 01580 Grade AR
Purity 99% CAS No. 5908-99-6
Molecular Formula C34H48N2O10S.H2O Molecular Weight 694.83
H.S. Code 3004.4910 Shelf Life 60 Months

Physical Properties

Physical state at 20 °C Solid Colour White crystalline
Melting point/ Freezing point [°C] 192°C Solubility in water [% weight] 2.500 g/l at 4 °C

Specifications

Appearance Colourless crystals or a white crystalline powder; odourless Assay (Potentiometric; on anhydrous basis) 99.0 - 101.0%
Identifications To comply IP tests pH (2% w/v solution) 4.5 to 6.2
Related substance (by HPLC) Individual impurity Max 0.3%
Sum of all impurities Max 0.5% Specific optical rotation (10% w/v solution) -0.50° to +0.05°
Apoatropine (absorbance of a 0.1 per cent w/v solution in 0.01 M hydrochloric acid at about 245 nm) Max 0.4 Foreign alkaloids and decomposition products (by TLC) To comply IP test
Sulphated ash Max 0.2% Water (by KF) Max 4.0%

Safety Information and Hazard Symbols

Skull and Crossbones
Symbol: GHS06
 Signal Word: Danger
 UN No.: 1544
 IMCO Class No.: 6.1
 Packing Group: II
 Hazardous Statement: H300-H330
 Precaution Statement: P260-P264-P284-P301 + P310-P310
Revision Date: 22-Jan-2021

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