|
Appearance
|
White crystalline powder
|
|
Solubility
|
Soluble in Methylene chloride, sparingly soluble in methanol & acetone. Insoluble in water
|
|
Identification
|
|
|
By IR
|
Spectrum of sample should be concordant with the IR spectrum of reference standard
|
|
By HPLC
|
The RT of sample should match with RT of WS
|
|
Clarity ( 5% solution in dichloromethane)
|
Clear solution
|
|
Melting range
|
76.0-78.0°C
|
|
Loss on drying
|
NMT 1.0%
|
|
Chromatographic purity (by HPLC)
|
Min 98.0%
|
|
Related Substances
|
|
|
4-Hydroxypropiophenone
|
NMT 0.01%
|
|
Bromohydroxypropiophenone
|
NMT 0.01%
|
|
Dibromohydroxypropiophenone
|
NMT 0.01%
|
|
4-Benzyloxypropiophenone
|
NMT 2.0%
|
|
Dibromobenzyloxypropiophenone
|
NMT 2.0%
|
|
Maximum other impurity
|
NMT 2.0%
|
|
Sum of impurities
|
NMT 3.0%
|
|
Purity (by HPLC)
|
NLT 98.5%
|
|
Metallic impurity-aluminium
|
Not detected
|